In the REMAP study (REplacement of MAle mini-Puberty), Papadimitriou et al described the administration of daily injections of Pergoveris (LH/FSH 75/150 IU) for 3 months to 10 infants, median age 4.2 months, with micropenis and/or cryptorchidism due to CHH (315). Here, PLOD1 is linked to cryptorchidism.