TNF and cancer: Zeng et al. [46] found that scutellarin reduced the expression levels of TNF-α and TNF-1β in mouse serum, up-regulated the expression of BAX, and down-regulated the expression level of Bcl-2 in mouse cancer tissues through down-regulation of the Wnt/β-Catenin signaling pathway, and then inhibited the proliferation and migration of HT-29 cancer cells, and induced cell apoptosis.