Recent studies demonstrate that STK3 acts as a tumor suppressor, restricting tumor size and metastasis in the hepatic cell cancer [11], pancreatic duct cancer [25], breast cancer [26], and colorectal cancer [27, 28] while exhibiting malignant potential in the gastric cancer [29] and prostate cancer [30]. The gene discussed is STK3; the disease is pancreatic ductal adenocarcinoma.