Of note, CTRP3 was observed to represent an equally valuable predictor of CCS (AUC = 0.808; sens = 70.8%, 1-spec = 20.8% for cut-off 51.05 ng/mL CTRP3), ACS-1 (AUC = 0.798; sens = 70.8%, 1-spec = 20.4% for cut-off 51.25 ng/mL CTRP3), and ACS-2 (AUC = 0.827; sens = 70.8%, 1-spec = 18.2% for cut-off 50.50 ng/mL CTRP3) (Fig. 5B and Tab. The gene discussed is C1QTNF3; the disease is Apert syndrome.