Interestingly, we found higher circulating CTRP3 levels in Ldlr ̄/ ̄ (365.2 ± 23.8 ng/mL) mice after HFD-induced atherosclerosis than in controls (193.9 ± 27.3 ng/mL, Fig. 6A), which is contrary to our observations regarding the levels in CAD patients (Fig. 1). Here, C1QTNF3 is linked to atherosclerosis.