MYZAP and familial dilated cardiomyopathy: This phenotype is coincident with 2 homozygous LoF cases recently reported.5 Unlike the previous report, affected individuals in our family exhibited LoF in compound heterozygosity, providing further support to MYZAP as a recessive DCM-associated gene and suggesting that the relevance of MYZAP variants in DCM may be higher than previously anticipated.