MPO and peptic ulcer disease: de Almeida et al. (2017) reported a total reduction of gastric lesions areas by using Myrcianthes pungens fruit and leaf extract administrated with 100 mg/kg of IND in female Swiss mice. Essential oil of Melaleuca quinquenervia inhibited GHS depletion and decreased MPO activity and MDA levels in a female Sprague-Dawley rat model of ethanol-induced peptic ulcers (Cilingir-Kaya & Gurler, 2021).