A study used cholesterol TEG to insert antisense oligonucleotides (ASOs) targeting STAT6 into exosomes and found that exoASO‐STAT6 can effectively target TAMs and induce M2 macrophages to differentiate into the M1 phenotype, leading to a remodeling of the tumor microenvironment and a CD8 T cell‐mediated adaptive immune response.126. Here, STAT6 is linked to neoplasm.