NLGN3 and Alzheimer disease: In a recent study[116] using a newly developed NeuroDex ExoSort kit that employs immunoaffinity capture on magnetic beads with antibodies against growth-associated protein 43 (GP43) and Neuroligin (NLGN3), highly enriched neuron-derived EVs (NDEVs) were isolated from the plasma of control and Alzheimer Disease (AD) patients.