Using multivariate logistic regression analysis, diabetes, body mass growth rate ≥5.54%, TG ≥1.40 mmol/L, NT-proBNP ≥5.82 ng/L, SBP-SD ≥13.52, SBP-CV ≥ 8.63, DBP- SD ≥8.14, and DBP-CV ≥8.82) were risk factors for MACCE in uraemia patients with hypertension, and the differences were statistically significant (p<0.05) as shown in Table 3. This evidence concerns the gene NPPB and diabetes mellitus.