Recent studies show the presence of aggregates of WTp53 or its mutant forms in several cancer cell lines and tumour biopsy samples indicating a possible link between p53 aggregation and cancer pathogenesis (Ano Bom et al., 2012; De Smet et al., 2017; Freed-Pastor and Prives, 2012; Kanapathipillai, 2018; Levy et al., 2011; Pedrote et al., 2020; Silva et al., 2014; Xu et al., 2011). The gene discussed is TP53; the disease is cancer.