The results showed that sarcopenia (HR=1.577, 95%CI: 1.181-2.106, P=0.002), AFP ≥ 200 ng/mL (HR=1.361, 95%CI: 1.024-1.809, P=0.033), multifocal tumor (HR=1.423, 95%CI: 1.066-1.899, P=0.017), and maximal tumor diameter (HR=1.075, 95%CI: 1.041-1.110, P<0.001) were independent risk factors for PFS (Table 4). The gene discussed is AFP; the disease is sarcopenia.