We found that the expression levels of GSDMB, GSDMD, GSDME, and DFNB59 were significantly correlated with the immune subtypes of HCC (p < 0.05), except for the missing information of GSDMA, while none of the expression levels of GSDMs could be directly correlated with the molecular subtypes of HCC. Here, GSDME is linked to hepatocellular carcinoma.