We found that the expression levels of GSDMB, GSDMD, GSDME, and DFNB59 were significantly correlated with the immune subtypes of HCC (p < 0.05), except for the missing information of GSDMA, while none of the expression levels of GSDMs could be directly correlated with the molecular subtypes of HCC. The gene discussed is GSDMA; the disease is hepatocellular carcinoma.