PGAM1 and cancer: Using the CPTAC dataset, we found that phosphorylation of the PGAM1 S118 site was higher in cancers such as BRCA, COAD, and ccRCC compared to normal tissues, while phosphorylation of the PGAM1 S31 site was higher in cancers such as PAAD, LUSC, LUAD, HNSC and HCC compared to normal tissues (Figure 2A).