CRP and infectious disease: In fact many factors have been identified as biomarkers of Kawasaki disease, such as inflammatory biomarkers such as white blood cells (WBC), C-reactive protein (CRP) and procalcitonin (PCT), immunomarkers, proteomic markers, and genomic markers, but the common problem with these markers is that they have low sensitivity or specificity, and are of limited value when used individually to discriminate between KD and infectious diseases in children (12).