No significant differences in sex; age; BMI; NLR; the presence of viral hepatitis; PLT count; AFP, ALB, TBIL, ALT, and AST levels; PT; Child–Pugh score; the presence cirrhosis; and the presence of hypersplenism were found whether in the total, PSM, or IPTW cohorts (Tables 1–3). The gene discussed is ALB; the disease is Cirrhosis.