On the other hand, the European Academy of Andrology (EAA) in guidelines from 2018 postulates evaluation of total T, FSH and LH in every case of an infertile man with oligoasthenoteratozoospermia (OAT).61 These recommendations are in line with the guidelines of the European Society Urology (EAU) from 2021.11 However, it is believed that the remaining hormonal tests should be performed based on an individual assessment of the patient. Here, PLOD1 is linked to Infertility.