It revealed that female age (OR=1.13; 95% CI=1.01-1.15; P < 0.001), female BMI (OR=1.05, 95% CI=1.01-1.09, P=0.008), number of spontaneous abortions (OR=1.24, 95% CI=1.04-1.47, P=0.015), number of induced abortions (OR=1.08, 95% CI=0.93-1.24, P=0.325), basal FSH (OR=1.02, 95% CI=0.99-1.06, P=0.214), endometrium thickness on hCG day (OR=0.98, 95% CI=0.94-1.02, P=0.345) and number of Good quality embryos (OR=0.94, 95% CI=0.90-0.99, P=0.021) were independent prognostic factors for early miscarriage for total patients. Here, BRD2 is linked to Miscarriage.