In both AD and PSO, SGs continued to express genes encoding key proteins for lipid metabolism and transport such as ALOX15B (Figures 3C, D), APOC1, FABP7 (Figures 3E, F), FADS1, FADS2, FASN, PPARG, or RARRES1 among others at high levels (Supplementary Table S4). Here, FADS2 is linked to Alzheimer disease.