FADS2 and Alzheimer disease: We also confirmed the central role of genes involved in lipid synthesis (FASN, THRSP, and ELOVL5), metabolism (FADS2 and ACSBG1) and transport (APOC1), and keratinization (KRT79), which were found to be expressed in a combined subpopulation of healthy, L and NL AD inner root sheath and SG cells (40).