After ischaemic kidney injury, dilated renal lymphatic vessels express high levels of CCL21, which stimulates the recruitment of more CCR7+ DCs to renal draining lymph nodes, worsening renal inflammation and fibrosis, and inhibiting CCR7 expression (blocking the binding of VEGF-C/D to VEGFR3) or renal lymphangiogenesis reduces the migration of CCR7+ DCs (73). Here, CCR7 is linked to urogenital neoplasm.