We observed that absence of cardiovascular disease (OR: 0.23, 95% CI: 0.09 - 0.57; p = 0.002), low IL-6 (OR: 0.21, 95% CI: 0.12 - 0.36; p < 0.0001) and PCT levels (OR: 0.27, 95% CI: 0.14 - 0.52; p < 0.0001) and TLR4 rs4986790 AG or GG genotype (OR: 0.47, 95% CI: 0.23 - 0.96; p = 0.039) remained independent protective factors (Table 3). The gene discussed is TLR4; the disease is cardiovascular disorder.