For instance, it has shown the ability to enhance chemotherapy sensitivity in pancreatic cancer by inhibiting NF-κB activation induced by chemotherapy.510 Additionally, pomalidomide has demonstrated the capacity to suppress NF-κB levels and significantly reduce cortical neuron apoptosis by regulating Bax, cytochrome c, and poly (ADP-ribose) polymerase. This evidence concerns the gene NFKB1 and familial pancreatic carcinoma.