Zhou et al., found that galectin-3 can activate TLR4 signaling and promote NF-κB translocation through the induction of lncRNA-NEAT1 (nuclear enriched abundant transcript 1) to facilitate lung adenocarcinoma cell proliferation.255 MicroRNAs, particularly miR-505, has also been reported to inhibit lung cancer proliferation through AKT/NF-κB pathway.256. The gene discussed is NFKB1; the disease is lung adenocarcinoma.