Meanwhile, the mRNA levels of KIF15 detected in another HCC cohort incorporating 120 tumoral and paired non-cancerous tissues were shown to be significantly overexpressed, which was also demonstrated to be independently correlated with worse OS and increased risk of recurrence, as well as a close relationship with several clinicopathological parameters, including tumor size, single or multiple, TNM stage, vascular invasion, and encapsulation status [104]. The gene discussed is KIF15; the disease is hepatocellular carcinoma.