Additionally, based on the correlation analysis between KIF21B expression and matched pathological features of 186 HCC patients, it was disclosed that high KIF21B expression was significantly associated with vascular invasion, TNM stage, and HBsAg status, indicating the utility of KIF20A as an independent risk factor for poor OS and DFS in patients with HCC [70]. Here, KIF21B is linked to hepatocellular carcinoma.