In this process, High Mobility Group AT-Hook 1 (HMGA1), also known as an oncogenic transcription factor that participated in the regulation of multiple cancer-related genes (such as STAT3, MMP2, E-cadherin, Vimentin, and Twist1) transcription via binding to their promoter regions, was identified as an interactor of KIFC1 by co-IP assay. The gene discussed is HMGA1; the disease is cancer.