IL2RA and myeloid sarcoma: Overlapping results have been also obtained in MS, in which the rs2104286 polymorphism in the IL-2RA locus has been associated with a higher risk of developing the disease and with increased expression of IL-2Rα on naïve Th cells, which preferentially differentiate into encephalitogenic granulocyte-macrophage colony-stimulating factor–producing effector Th cells (121, 126).