A recent meta-analysis found acute respiratory distress syndrome and acute kidney injury as factors predicting admission to ICU; and shortness of breath, neurological symptoms, raised CRP level, and D-dimer level as predicting factors for progression to severe or critical disease and death.44 These factors will be useful for designing models predicting hospital and long-term outcomes of children with COVID-19. The gene discussed is CRP; the disease is glycogen storage disease VI.