The KEGG pathway enrichment demonstrated significant enrichment of DEGs in interleukin 17 (IL-17) signaling pathway, T helper 17 (Th17) cell differentiation, malaria, African trypanosomiasis, nuclear factor κB (NF-κB) signaling pathway, rheumatoid arthritis, advanced glycation end products (AGEs)-receptor for AGE (RAGE) signaling pathway in diabetic complications, tumor necrosis factor (TNF) signaling pathway, transcriptional misregulation in cancer, pertussis among others (see Supplementary File 4B). This evidence concerns the gene TNF and rheumatoid arthritis.