From Bonferroni post-hoc test, T2DM patients exhibited, in comparison to NGT subjects, a worsening of insulin sensitivity as evidenced by Matsuda/index (p < 0.0001) and inflammatory profile as shown by hs-CRP (p < 0.0001), higher MPV values (p < 0.0001), increased PLT count (p < 0.0001). Here, INS is linked to type 2 diabetes mellitus.