Additionally, we have revealed that 1) GDI2 shares common genetic variation with telomere length and may play an essential role in telomere biology; 2) NT5C may play a role in cardiac diseases; 3) endoplasmic reticulum-associated cellular components and nucleotide metabolism may be involved in the mechanism of telomere length regulation of target genes; and 4) acetylsalicylic acid and ginseng have inhibitory effects on MYC and IL-6 (the interacting proteins of target proteins), respectively; 58–64-0 and caffeic acid have potential as target compounds for telomere length regulation. Here, NT5C is linked to heart disorder.