UBQLN1 and neoplasm: Xu et al. showed that overexpression of UBQLN1 in most cases implied the poor prognosis of hepatocellular carcinoma [31].Wang et al. discovered that the overexpression of UBQLN1 was found in breast cancer (BC) tissue, which was associated with tumor size, lymph node metastasis, TNM stage, vascular invasion and poor prognosis of BC patients [30].