Additionally, there are no obvious differences of positive ratio among gender, age, clinical stage, lymph node metastasis, distant metastasis, ALK mutation status, EGFR mutation status and PDL1 expression (P>0.05) (Fig. 6c-d, f-k) except diameter (Fig. 6e, Table 4) between high UBQNL1 expression and low UBQNL1 expression. The gene discussed is CD274; the disease is metastatic malignant neoplasm in the lymph nodes.