Ning et al. disclosed that reduced JMJD1A expression in gastric cancer is associated with invasive phenotypes and poor prognosis, and this association is further substantiated by a positive correlation between JMJD1A and RUNX3 expression, indicating that reduced RUNX3 expression serves as an indicator of unfavorable prognosis [93]. The gene discussed is KDM3A; the disease is gastric cancer.