LAYN and head and neck squamous cell carcinoma: Survival analyses revealed that high LAYN expression worsened the overall survival (OS) of HNSCC patients (Fig. 1C) (HR = 1.3, P < 0.05), while no difference existed in disease-free survival (DFS) with two curves intersecting between the LAYN-high and LAYN-low groups (HR = 1, P = 1) (Fig. 1D).