Sandoval-Garcia et al. (n = 1,066, Edinburgh Type 2 Diabetes Study) found that in those with diabetes, increasing fractal dimension was associated with decreased stroke risk in fully adjusted models, including when adjusting for CRP and diabetic retinopathy (HR: 0.7, 95% CI 0.51–0.94, p = 0.02) [32]. This evidence concerns the gene CRP and diabetic retinopathy.