At the T2 visit, cohort 1 had significantly higher levels of fasting plasma glucose (FPG), 1-h plasma glucose (1hPG), 2-h plasma glucose (2hPG), fasting insulin (FIns), 1-h insulin (1hIns), 2-h insulin (2hIns), homeostasis model assessment for β-cell function (HOMA-β), and homeostasis model assessment for insulin resistance index (HOMA-IR) than the control cohort (P < 0.05), while cohort 2 only had higher FPG levels than the control cohort (P < 0.05). This evidence concerns the gene INS and Insulin resistance.