Based on RNA‐seq profiling data, we aimed to decipher subtype‐specific gene patterns and putative target genes of GRHL3 in SCaBER and EJ28 tumor cells and identified GRHL3‐regulated differential expressed gene (DEG) sets (adjusted P ≤ 0.05) comprising n = 263 genes in EJ28 and n = 86 genes in SCaBER clones (Fig. 6A,B and Tables S10 and S11). The gene discussed is GRHL3; the disease is neoplasm.