Overall, ABBV-399 has shown encouraging efficacy in treating relapsed/refractory nonsquamous NSCLC with c-MET overexpression and wild-type EGFR, but further studies will be needed to validate its efficacy in patients with squamous NSCLC and EGFR-mutant NSCLC. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.