After 3% NaCl treatment, the body weight decreased significantly along with a significant increase in urine volume, the plasma albumin level increased significantly and returned to normal, the hemoglobin concentration and hematocrit level decreased significantly, and there was no significant change in serum sodium and potassium levels before and after treatment, no infants developed hypernatremia after 3% NaCl treatment (Table 3). The gene discussed is ALB; the disease is Hypernatremia.