We observed a similar depletion of lipid reserves in a C-26 mouse cachexia model; furthermore, the beta-oxidation gene Carnitine Palmitoyltransferase 1A (CPT1A, the mammalian homologue of Whd) is negatively correlated with muscle quality in cachectic patients with pancreatic ductal adenocarcinoma. The gene discussed is CPT1A; the disease is pancreatic ductal adenocarcinoma.