We conducted a pan-cancer Kaplan–Meier survival analysis for ALOXE3 and found that it serves as a better prognostic indicator in glioblastoma multiforme (GBM), while it is associated with unfavorable outcomes in colon adenocarcinoma (COAD) and uterine corpus endometrial carcinoma (UCEC) (Fig. S6). This evidence concerns the gene ALOXE3 and glioblastoma.