With decreasing ejection fractions, levels of LVEDD, LDL-C, sST2, and NT-proBNP progressively increased; there were no statistical differences among the 3 groups concerning heart rate, history of hypertension, systolic pressure, diastolic pressure, smoking history, history of coronary heart disease, and diabetes (P > .05), as indicated in Table 2. This evidence concerns the gene COG2 and hypertensive disorder.