APLP2 and Alzheimer disease: For example, in our study, we found four probe sets mapping to genes implicated in neurological diseases such as AD, including Homeodomain Interacting Protein Kinase 2 (HIPK2) [66] and platelet-activating factor acetylhydrolase 1b (PAFAH1B1) [67], and three probe sets mapping to genes including BIN1 [68, 69], APLP2 [70, 71], and VCAN [72], more specifically in males.