We used zebrafish xenograft models of ovarian cancer (OVCAR-5) and rhabdomyosarcoma (RD), together with EpCAM Chimeric Antigen Receptor (CAR-T) cells or epidermal growth factor receptor (EGFR)/CD3 bispecific T cell engagers (BiTEs), respectively. Here, EPCAM is linked to rhabdomyosarcoma.