RPIA and hyperinsulinemic hypoglycemia, familial, 4: An enrichment analysis (Fig. 3) of the 18 metabolites that characterise neuroinflammation in CSF collected from this South African paediatric HIV cohort shows that our set of metabolites is closely associated with that of a biotinidase deficiency, ribose-5-phosphate isomerase deficiency, and propionic acidemia.