M1 macrophages, which express high levels of pro‐inflammatory cytokines and MHCII are referred to as anti‐tumor, whereas M2 macrophages, which express high levels of immunosuppressive factors such as IL‐10 and transforming growth factor (TGF)‐β are referred to as pro‐tumorigenic.82 The gene discussed is IL10; the disease is neoplasm.