PTGS2 and VEGF signalling pathway genes, including VEGFA, VEGFB, KDR, CXCR1 and CXCR2, were found to be highly expressed in tumour samples compared to their paired normal tissues in the Cancer Genome Atlas for Head and Neck Squamous Cell Carcinoma (TCGA‐HNSCC) datasets, with CXCR2 being the only exception, with higher expression in normal tissues than in tumour tissues.21 This evidence concerns the gene CXCR1 and neoplasm.