Fasting and post-OGTT plasma glucose concentrations declined by 33 and 73 mg/dL, respectively; insulin secretion (Δ C-Pep0–120/Δ G0–120) increased 2-fold; and β cell function (disposition index) (Δ C-Pep0–120/Δ G0–120/insulin resistance) rose 2.4-fold, where C-Pep is C-Peptide and G is glucose. This evidence concerns the gene INS and Insulin resistance.