The resulting mice were deficient in autophagy only within the hepatocytes of the liver (B6 Albumin-KO) and were used as recipients along with the littermate Atg5fl/fl (B6 WT) controls in the BALB/c into B6 MHC-mismatched model of GVHD as described above and in Methods. The gene discussed is ALB; the disease is graft versus host disease.