On immunostaining of RA synovium, most of the CD14+ synovial macrophages highly expressed NFAT5 but failed to express SAA (Figure 1G); the correlation coefficient for colocalization analysis was 0.73 between CD14 and NFAT5 and 0.19 between CD14 and SAA (Figure 1H). This evidence concerns the gene NFAT5 and rheumatoid arthritis.