To determine whether the function of PBRM1 is conserved in human uterine stromal cells, we reanalyzed human uterine stromal single-cell RNA-Seq data from women who underwent elective termination of normal pregnancies (age, 25–35 years old; gestational age, 7–9 weeks) without a history of miscarriages (43). Here, PBRM1 is linked to spontaneous abortion.