However, in another study, decreased plasma levels of IL‐4 were seen in HD, but no significant differences in IFN‐γ, IL‐1β, IL‐2, IL‐6, IL‐8, IL‐10, IL‐12p70, IL‐13, or TNF‐α were reported [12]. This evidence concerns the gene CXCL8 and Huntington disease.