ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; CALM, clathrin assembly lymphoid myeloid; CLL, chronic lymphocytic leukemia; CML, chronic myeloid leukemia; CRC, colorectal cancer; DLBCL, diffuse large bB‐ cell lymphoma; KMT2A‐r, KMT2A‐rearranged; MM, multiple myeloma; NPM, nucleophosmin; NSCLC, non‐ small‐ cell lung cancer; PDAC, pancreatic cancer; SLL, small lymphocytic lymphoma. The gene discussed is KMT2A; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.