In contrast, CBX2 [29, 30], CBX7 [5, 6, 17, 34, 35], and CBX8 [16, 36, 37, 38, 39] have oncogenic potential in hematopoiesis as they promote the survival of leukemia [5, 6, 16, 29, 30, 35, 36, 37] and lymphoma [17, 38, 39] cells. The gene discussed is CBX8; the disease is leukemia.