Considering the potential role of ANGPTL2 on NOX signaling that we previously described in the vascular endothelium of KD mice (Yu et al., 2015), and the contribution of NOXs in cardiac hypertrophy, fibrosis and progression towards heart failure [for review, (Bedard and Krause, 2007)], we investigated NOX expression in hearts from WT and KD mice. The gene discussed is ANGPTL2; the disease is cardiac hypertrophy.